Players take turns rolling the die and asking each other questions from the cards. If a question is answered correctly, the card is won; if answered incorrectly, the card is returned to the bottom of the pile. The player with the most cards at the end of the game is the winner.
Players have a few chances throughout the game to get a Noggin's Choice card. This means they can choose a card from any other player, and get ahead. Remember the correct answers. If a question is not answered correctly the first time, that question will come up again.